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Bengaluru, 1st March, 2019: Summer is that time of the year wherein many viral infections occur. In fact, this year, the mercury levels have soared further up due to global warming. This early onset of summer coupled with high temperatures during days and relative cooler nights is taking a toll on the health of Bengalureans. The change in the climate is already causing flu like respiratory infections and food related infections. Elaborating about the impact of rising temperature, Dr. Mahesh Kumar, Consultant Internal Medicine, Narayana Health City said, "Climatic changes challenges our immune system and can trigger various illnesses. However, the early onset of summer and high temperature seems to be adversely affecting our health. We are already witnessing a 15% increase in the number of patients with viral infections. The pattern of temperature also seems to be impacting our health. The nights are cooler and the days are extremely hot making it difficult for the body to adjust to the change. There is an increase in the number of patients suffering from conditions like influenza and viral respiratory infections like bronchitis. We are also noticing a surge in food and water borne infections as well. "Further, what is more alarming this year is the intensity. The infections seems to be more severe in nature." added Dr. Mahesh Kumar While some of the conditions are unavoidable, a majority of these issues can be tackled by improving our body's immunity, exercise, healthy diet and preventive measures. Some of the preventive measures that one could take to protect oneself from infections are: 1. Stay hydrated - Drinking 2.5 to 3 liters of water every day would improve the muscle hydration and prevent muscle aches, pains and fatigue which is common in peak summer. 2. Avoid packed and refrigerated food- Eat fresh homemade food as much as possible. Eating refrigerated, stored and packaged foods would invite frequent infections and also more stomach related ailments like indigestion and gastritis 3. Make exercising an integral part of the daily routine- Starting the day with exercise will be more refreshing, improve both the absorption and retention of vit d in bones and muscles. Vitamin D also boosts our body's immunity. 4. Regular vaccination- Influenza and typhoid vaccinations to susceptible individuals would definitely help not only the individuals, but also prevent further spread of the infections in the community and prevent both morbidity and frequent use of antibiotics.
Bengaluru: As per the research done by India Against Cancer, In India more than 2 million people are living with cancer and a majority of them do not have access to quality diagnosis and care. To bridge the accessibility gap, Narayana Multispecialty Hospital, Whitefield has launched a dedicated oncology department in its campus. The department was inaugurated in the presence of Shri. N Santosh Hegde, Former Supreme Court Judge and Lokayukta of State of Karnataka, and Dr. Sharat Damodar, Clinical Director-Mazumdar Shaw Medical Center and Sr. Consultant Hematologist & Head - Bone Marrow Transplant Unit, Narayana Health City. Speaking about the facility, Dr. Sharat Damodar, Clinical Director - Mazumdar Shaw Medical Center and Sr. Consultant Hematologist & Head - Bone Marrow Transplant Unit, Narayana Health City, said, 'Apart from timely diagnosis, cancer care in India is mired with accessibility. With our newly launched department, we hope to bridge this gap and provide easy access to comprehensive quality cancer care to the residents in the peripheral areas of the city." "The department is also equipped with a tumor board wherein doctors of different specialties come together and identify the best possible treatment plan for each individual patient. The facility helps to provide patients with holistic care as well as better treatment outcome." added Dr. Sharat The dedicated department will offer medical Oncology, surgical Oncology and haematological facilities for all types of cancer. The special wing will have specialist doctors for Medical Oncology, Musculo Skeletal Oncology, Radiation Oncology, Onco- Gynaecology, Oncology Breast & Oncoplastic and Oncology- Head & Neck Surgery. The occasion also witnessed the launch of cancer screening package and free mobile mammogram campaign. The free mammogram will be help women residents in the area to check for breast cancer. The free screening will be held in the hospital premises from 11th January to 12th January 2019. The number of cancer cases in India is increasing every year. According to WHO's Cancer Report, in India, lung, oral, lip, throat and neck cancers are the most common among men while women suffer more from cervix, breast and ovarian cancers. In the elderly, the most commonly occurring cancers are kidney, intestine and prostate cancer. Narayana Multispeciality Hospital, Whitefield has expertise in handling medical emergencies with specialist doctors and staff empanelled, who are available 24X7 and throughout the year. Equipped with world class infrastructure and a multi-disciplinary team, Narayana Multispeciality Hospital, Whitefield has the capability to treat any kind of emergencies like cardiac, neuro or any other speciality. The hospital also has a fully equipped ICU and ER, making it one of the preferred territory care hospital in the area.
68 year old man from Bangalore, got a new life as he underwent heart and lungs transplant at Narayana Health City, Bangalore. The donor is a 24yr old male from Bangalore who met with a road accident. He was admitted at City Hospital. Doctors declared him 'Brain Dead' and the family consented in the presence of Jeevasaarthakathe for organ donation to save many lives. The recipient, Mr. Kasim Shariff, retired from Central Govt Services was first diagnosed with age related lung disease in 2016 in a city hospital and he was on a routine treatment for his medical condition. His condition eventually deteriorated further and he was diagnosed with End Stage Lung Disease for which lung transplant was the only solution. His search for quality treatment brought him to Narayana Health City, Bangalore, 6 months ago. When Narayana Health doctors conducted full body check-up, he was also diagnosed with severe Coronary Artery Disease. As his health condition was not suitable for Bypass Surgery, the patient was registered at the state nodal agency 'Jeevasaarthakathe' in Nov'18 for Heart and Lungs. Speaking about the case Dr. Julius Punnen Senior Consultant, Cardiothoracic and Transplant Surgeon at Narayana Health City said, 'Heart and lungs function in tandem to supply and deliver oxygen to the rest of the body, which makes this transplant more complicated than single organ transplant. For this transplant organs were retrieved as a bloc and transplanted to the recipient's body. Such requirements and conditions are rare in our country. The surgery is successful and the patient is responding to the treatment positively.' 'The standard window period for the donor organs is 4 hours. Bangalore Traffic Police supported us with Green Corridor, and the organs were transported within 40 mins, travelling a 62 kms stretch. Without their support, this transplant would not have been possible. Lung transplant is complicated, risky and the chances of infections are higher and in this case we were doing bloc transplant which made the surgery more complex. The patient will be under observation in ITU for next few days to avoid any complications.' said Dr. Basha Khan, Senior Consultant Pulmonology/Intensive Care and Medical Director-Lung Transplant, Narayana Health City Sharing her experience, patients wife said, 'My husband has been dealing with serious health concerns from past three years and things got more complicated in the last couple of months. We went to so many hospitals for right diagnosis but our efforts were mostly in vein. I am grateful we came to Narayana Health City for advise otherwise we might have lost him due to lack of knowledge of his heart condition. We are lucky that within three months of registration at Jeevasaarthakathe we found a matching donor. Team of doctors and administrative staff at Narayana Health City have been extremely helpful and supportive to my husband and my family.' The heart and lungs retrieval and transplant was performed by Dr. Julius Punnen- Senior Consultant Cardiothoracic and Transplant Surgeon, Dr. Varun Shetty- Consultant Cardiothoracic and Transplant Surgeon, Dr. Bagirath Raghuraman, Senior Consultant, Program Director Heart Transplant, Dr. Vijay C L, Consultant - Thoracic Surgery, Dr. Govardhan Reddy Associate Consultant - Cardiothoracic Surgery, Dr. Inaythulla Khan, Associate Consultant - Cardiothoracic Surgery. Team of Physicians led by Dr. Basha Khan - Senior Consultant Pulmonology/Intensive Care and Medical Director - Lung Transplant, Dr. Syed Tousheed - Consultant Pulmonology and Dr. Murali Mohan Senior Consultant - Pulmonology, all at Narayana Health City, Bangalore
A 37 year old police officer from Oman, Muscat was suffering from chronic heart failure with frequent exacerbations and recurrent hospitalisations since the last 3 years. His search for quality treatment brought him to Narayana Health City, Bangalore. A comprehensive evaluation revealed that his left ventricular function was just 15% (Normal Left ventricular function is 55%). A cardiac catheterisation test was performed and based on the data, he was not a suitable candidate for cardiac transplantation. In view of his clinical condition, he was advised to undergo Left Ventricular Assist Device (LVAD) implantation. LVAD is a battery-operated, mechanical pump device that is surgically implanted. The LVAD device connects the patient's failing left ventricle to the aorta. It draws out blood for the patient's weakened left ventricle and pumps it into the patient's aorta. An important pre-requisite for implantation of an LVAD is a normal right ventricular function, since the LVAD can support only the failing left ventricle. Patients who suffer from biventricular failure (failure of both left and right ventricles) are not suitable candidates for LVAD implantation and are advised to undergo BiVAD or Total artificial heart (TAH) surgery. This patient's LVAD implantation surgery was successful and was funded by the Royal Oman Government. Speaking about the case, Dr. Bagirath Raghuraman, MD, DM (Cardiology), Program Director Heart Transplant at Narayana Health City said, "Mechanical circulatory support devices have become important options in the management of both acute and chronic heart failure conditions. Its value can be gauged from the fact that it is available off the shelf at short notice and is lifesaving in those patients on life support equipment waiting for a donor heart. Apart from this, LVAD is also an option for heart failure patients who are at the other end of the spectrum who are not suitable for a heart transplant due to very high pulmonary artery pressures, like this patient. We are glad that this patient has responded very well to the LVAD device. His condition has improved dramatically from the time he was admitted and now he can manage his work on his own. We will continue to monitor the patient periodically". Dr. Julius Punnen, Senior Consultant Cardiothoracic and Transplant Surgeon at Narayana Health City who operated on this patient added "The worldwide prevalence of patients living with chronic heart failure is on a rise. With severe and chronic heart failure, the left ventricle weakens to the point that it can no longer pump enough blood on its own. Then we use LVAD to save these situations. The procedure to implant LVAD is complex and involves risks. However, LVAD can be lifesaving and can emerge as a ray of hope for many patients. We will monitor the patient periodically. Over a period of time, his pulmonary artery pressures will decrease and he may become suitable for a cardiac transplant". Dr. Varun Shetty, Consultant Cardiothoracic and Transplant Surgeon at Narayana Health City who also operated on this patient said "Since their inception, there have been marked improvements in the design and technology of the LVAD's making them a reliable therapeutic option for patients with advanced heart failure. The LVAD's available today are technologically far superior to their predecessors. A decade ago, LVAD's required to be charged once in 4 hours. However, the LVAD's available today can work up to 11 hours after a single battery charge" Sharing his experience the patient said, 'Being a cop is tough and everyone looks up to you for inspiration. When I started having difficulty in managing my day to day work, my life became a living nightmare. Eventually, I could barely complete two sentences without becoming breathless and I needed constant help. Finding the right diagnosis, right doctor and correct treatment option was a tough task and I am grateful that I came to Narayana Health City. Now after LVAD implantation, under the supervision of Dr. Bagirath and Dr. Julius and the entire team, I can independently perform all my daily routine tasks by myself and it has made me even more confident and optimistic towards life. ' The biggest advantage of LVAD's are that they are readily available when required, they do not require immunosuppressive medications or periodic cardiac biopsies and are extremely biocompatible thereby eliminating the risk of rejection. The advent of mechanical circulatory support devices like the LVAD's have not only made patients' life easier but also helped them live a happy and fulfilling life. More importantly, they can live independently with dignity and perform most of their daily tasks without depending on others for help.
3rd December 2018: Timely diagnosis & a successful intervention by the Cardiac team at Narayana Multispeciality Hospital, Jaipur helped avert a life-threatening situation in a 79-year-old patient hailing from Gangapur city. The patient suffered from carotid artery stenosis - blockage in the arteries that supplies oxygenated blood to the brain. "When the patient came to the hospital, he was partially bedridden. In the last 2-3 months, he had suffered recurrent episodes of falling down/fainting & injuring himself, every time he attempted to walk a few meters. When we took the patient's history, we found out that the patient had suffered a right-sided paralysis attack three years ago from which he had now recovered. These symptoms made us suspect that the brain was not receiving enough blood which was confirmed via diagnostic tests" said Dr. Anshul Patodia, Consultant - Cardiology at Narayana Multispeciality Hospital, Jaipur. DSA (Angiography) Test results revealed 100% blockage in the left carotid artery & 95% blockage in the right carotid artery. The blood flow to the brain was severely compromised & any further blockage would lead to immediate death. This made prompt treatment necessary. This case was extremely risky as previously the brain was surviving on minimal blood, it received from the right artery only. Opening of the blocked artery would lead to sudden rush of blood to the brain. If not managed well, this could cause enormous spike in blood pressure potentially leading to severe brain swelling, bleeding or even death. Also, while performing the procedure, if there was even a minor disruption in the blood flow to the brain - it could lead to on-table death. After evaluating all treatment options, right carotid artery stenting was found to be the most feasible & practical as the patient had multiple co-morbidities too. Despite it being an extremely risky case, where even a slight error could prove fatal, we took up the challenge & were successful added Dr. Patodia. The patient was taken to the hospital's cath lab & carotid artery stenting was swiftly & successfully performed. Through a small nick in the groin, a catheter helped deliver a metal stent with inflatable balloon which opened the blockage. Special measures were undertaken, including inserting special filters to avoid any dislodged blood clot from blocking blood flow to the brain and having interventional neurologist Dr. Prashant Singh throughout to ensure prompt action in case of any neuro-emergency. The patient recovered well & he could walk again without any difficulty, within 24 hours. "It has been seen that patients who have high risk factors or who have to undergo a complex surgery or intervention do best at specialized centers where the clinical & support team has a lot of experience. We are happy that the team could successfully perform the intervention and save the patient" said Dr. Mala Airun, Zonal Clinical Director, Narayana Multispeciality Hospital, Jaipur.
India is witnessing a greater number of incidences of Type-1 diabetes mellitus among children during the last two decades mainly in the absence of regular exercises and habit of taking unhealthy diets. The estimated number of commonest form of diabetes in children has increased in India at a rate of 3 to 5% per annum over the last 2 decades. It is observed that the lack of awareness amongst people in general and the denial to accept the diagnosis guilt amongst parents opens the doors to several myths and misguidance, which are in the form of false promises made by people who might be ignorant to the medical field themselves, thus increasing the incidence of diabetes related complications, and occasionally at times a fatal outcome. While parents of children with type 1 diabetes may also experience irritability and mood changes and unintentionally lose weight in kids, the primarily cause of such illness among kids are genetic factors, environmental factors, and disorder of the immune regulatory mechanism. Dr Abhishek Kulkarni, Consultant & Department Co-ordinator, Pediatric & Adolescent Endocrinology, SRCC Children's Hospital, Mumbai, Pediatric & Adolescent Endocrinology, SRCC Children's Hospital, Mumbai, said, "The care of a diabetic child should be a team effort, led by the pediatric endocrinologist, along with vital roles played by diabetes educators, counselors, pediatric nutritionists and support groups. It is a daunting task on the part of the medical and paramedical individuals, but it is not all gloomy out there." "Recent advances in insulin therapy provide opportunities of delivering exogenous insulin in ways which mimics insulin secretion patterns of the human body. The contemporary standard of care, the basal-bolus regime provides basal insulin cover throughout the day with intermittent injections of short acting insulin covering meal timings. This not only reduces the rate of complications due to diabetes, but also prolongs the life expectancy to match that of the reference population," Dr Kulkarni said. The recent advancement of technology in invention of insulin pumps has improved the quality of life of type 1 diabetics providing relative freedom from needle pricks, flexibility in their daily routines, opportunities to enjoy the freedom of physical exercise and intermittent snacking with timely insulin doses. Intensive insulin therapies either through multiple daily dose injections or continuous subcutaneous insulin infusion through the insulin pump are associated with significant reduction in diabetes related complications. Doctors and Physicians at SRCC Children's Hospital managed by Narayana Hospital are committed to undertake more and more advance research providing opportunities to explore and device modalities to provide better health care with promising outcomes to improve the lives of type 1 diabetic children. A silver lining will continue to exist in the gloomiest of corridors of the medical field, experts at SRCC Children's Hospital managed by Narayana Hospital believe. About SRCC Children's Hospital, managed by Narayana Health: is a multi-speciality hospital exclusively for children. Of the 207 beds currently operational, 87 have been allocated for Multispecialty Critical Care covering new-borns to adolescents. It has taken critical care to a higher level with the concept of Level IV care where a qualified team of Paediatric Intensivists will be able to provide Emergency Life Support (ELS) for children with failure of their vital organs including heart, lungs and kidneys. Also available are a team of specialists in Cardiac sciences, Neurosciences, Hematology- Oncology, infectious diseases, Endocrinology, Orthopaedics, ENT, Gastroenterology, diagnostics services and nephrology amongst others. About Narayana Hrudayalaya Limited : Founded in 2000 by Dr. Devi Prasad Shetty and headquartered in Bengaluru, Narayana Hrudayalaya Limited is one of the leading healthcare service providers in India, operating a chain of multispecialty, tertiary and primary healthcare facilities. The Company has a network of 23 hospitals and 7 heart centres across India and single hospital overseas at Cayman Islands with over 6,200 operational beds across all its centres and potential to reach a capacity of over 7,100 beds. About Society for Rehabilitation of Crippled Children (SRCC): SRCC registered under the Societies Act , 1860 and the Maharashtra Public Trust Act 1950. It was established in 1948 to start Children's Orthopaedic Hospital to assist children affected by polio. So far, SRCC has provided healthcare benefits to 100,000 children. It aims are to organise hospitals and clinics for diagnosis, care and treatment of disabled and other children needing any other medical treatment. To create and educate public opinion on the problem of such afflicted children. Its first effort was to establish the Children's Orthopaedic Hospital to look after children afflicted by poliomyelitis. As this crippling disease was gradually eliminated, the society started offering its services to children. For more information: contact Adfactors PR Abhishek Chawande: Mob: 96694516774/ 9820670345
Narayana Health City successfully treated a Bangalorean youth who suffered heart attack while at work. The patient, Mr. Mohammed Rafeek, 27 year old, was suffering from a coronary artery disease (CAD) with Acute Coronary Syndrome (ACS) and Triple Vessel Disease. 27 year old software professional, Mr. Rafeek was leading a normal life until recently. One day suddenly he developed chest pain and was rushed to a nearby hospital. It was found that Mr. Rafeek suffered heart attack for which he was given adequate treatment. However, the search for an advanced treatment facility led him to Narayana Health City. The expert team of doctors under the aegis of Dr. Sanjay Mehrotra, Senior Consultant - Cardiology, Narayana Health City did a complete evaluation of the patient's condition and found that he was suffering from coronary artery disease (CAD) with Acute Coronary Syndrome (ACS). He underwent a coronary angiogram which showed a blockage (stenosis) of 80% in one of the main arteries of the heart called Left Anterior Descending (LAD) and was planned for an angioplasty and stenting. Optical Coherence Tomography (OCT) is new technology which is used Near Infrared Light (NIR) to visualise the inside of the heart arteries. Optical Coherence Tomography allows ten times better visualization than Intravascular Ultrasound (IVUS) which has been a method used to see the inside of heart arteries for a long time. OCT gives a much better resolution and exact information about the nature of the plaque, extent of narrowing of the coronary artery and helps to choose the size and length of the stent better. Speaking about the case, Dr. Sanjay Mehrotra, Senior Consultant - Cardiology, Narayana Health City said, "India today is experiencing a rapid transition in the disease burden and is gradually moving towards a scenario where majority of the deaths are caused by lifestyle diseases. In order to combat the rising incidence, we need to strengthen preventive measures by adopting healthy habits. However, there are times when disease is already there and one needs to effectively treat the disease which needs proficient diagnosis and precise treatment. Technologies like optical coherence tomography help in treating such conditions with more precision." "In case of Mr. Rafeek, with the help of OCT we were able to evaluate the diseased portion of the artery clearly as in his case there was Ruptured plaque which precipitates a heart attack was present in an area which cannot be seen on conventional angiography and failure to do so would have resulted in incomplete coverage which in turn would have lead to complication of stent occlusion and repeat myocardial Infarction (heart attack)." added Dr. Sanjay. Sharing his joy, Mr. Rafeek said, "While I suffered heart attack, my wife was nearing her delivery date and it felt like everything around me is coming to an end. I never imagined that I would be back with my wife celebrating the birth of our child. Today, I am not only getting better but leading a normal life again, thanks to the Narayana Health City. I am so grateful to Dr. Sanjay and his team for giving me a new life specially using this new technology in my case. One thing that I have learned from my own personal experience is that there is a reason why our ancestors lived a healthy life, it simply because of the discipline they followed" Cardiovascular diseases (CVDs) are posing huge social and economic concerns in India, and the steady upswing in the mortality attributed to CVDs is challenging. To prevent India from becoming the heart disease capital of the world, there is a need to bring a necessary shift in social behaviour and instil 'healthy living' as a norm. The responsibility also lies with the medical fraternity to leverage newer techniques which can effectively manage the disease and improve clinical and patient outcomes, eventually reducing the burden.
Narayana Health City successfully treated three patients suffering from chronic liver disease through related donor liver transplant. The doctors sourced matching livers from the recipients' family members and carried out the transplants at Narayana Health City. Patients included 39 year old Sathish Babu, 44 year old Venkata Swamy Reddy and 12 year old Sugita Sathiyaseelan. Hailing from Dommasandra, Anekal 39 year old Sathish Babu was a known case of chronic liver disease owing to alcoholism. He was being treated at Narayana Health City where the doctors advised him to undergo a liver transplant. Luckily for Mr. Sathish Babu, his sister was found to be a matching donor. Mr. Venkata Swamy Reddy, a 44 year old farmer was diagnosed with chronic liver cancer for which he was being treated at Narayana Health City. As his condition was not improving, he had to undergo a liver transplant. Fortunately for Mr. Reddy, his brother was a perfect match. 12 year old Sugitha Sathiyaseelan, a student from SriLanka, was diagnosed with chronic liver disease and the search for advanced treatment led her family to Narayana Health City where she was being treated. After a prolonged medical management she was advised to undergo liver transplant for which fortunately, her father was found to be her matched donor. Speaking about CLD and the successful transplants, Dr. Sanjay Goja - Director and Clinical Lead, Senior Consultant and Head of Liver Transplant & HPB Surgery, Narayana Health City said, "Chronic liver disease (CLD) can lead to faster complications and higher mortality. The classic signs for CLD are severe jaundice, itching, excessive bleeding, stunted or retarded growth, bloated bellies, irritability and vomiting blood. About 8-20% of people with liver complications suffer from alcohol induced liver diseases and rest 70-80 % with other liver diseases. Liver diseases are not only common among high alcohol consumers but many non-alcohol consumers also suffer from liver complications due to high Body Mass Index (BMI)." Chronic liver disease (CLD) consists of a wide range of liver pathologies which include inflammation (chronic hepatitis), liver cirrhosis, and hepatocellular carcinoma. It is estimated that in India around 20000 people need liver transplant with hardly 800-1000 cases getting treatment. This may be attributed to the high cost of liver transplant surgery and lack of awareness amongst people apart from other social reasons due to which not many families opt for liver transplant. The relatives who are allowed to donate include mother, father, brothers, sisters, son, daughter, and spouse. Recently in the new gazette, grandparents have been included in the list of first relatives. In majority cases donors are usually the parents where two-thirds constitute the mothers and the remaining one-third being the fathers.
Bengaluru, 06 September, 2018: As we head closer to World Marrow Donor Day, Mazumdar Shaw Cancer Centre at Narayana Health City - one of the leading Blood and Marrow Stem Cell Transplant units in India highlights alarming cases of two Cambodian sisters aged 9 and 11 years; their hero and saviour being a 11-month-old sibling and half HLA matched father. With Bone Marrow Transplant being the only cure for Thalassemia, it becomes very important to find a matching donor for such treatment. "It is highly unlikely to find an unrelated donor for Cambodian descent patients as there is no Cambodian donor registry and number of Cambodian donors in other registries are almost negligible", informed Dr. Sunil Bhat, Head - Paediatric Oncology, Haematology and Bone Marrow Transplant at Mazumdar Shaw Cancer Centre, Narayana Health City. "Chances of a match with other ethnic backgrounds are extremely low", he added. It was a big shock for this couple from Cambodia to have two consecutive children - both girls, suffering from Thalassemia - a disease that requires life-long blood transfusion every few weeks. "Most of the affected patients usually die in the second to fourth decade of life", confirmed Dr. Sunil Bhat. Fortunately, almost eight years after the second child was born, the family was blessed with a baby boy who was normal and did not suffer from Thalassemia. The father being a doctor by profession had made every possible effort to provide the best care to both his affected daughters. However, it was getting difficult for him in Cambodia. Giving adequate, safe and effective blood transfusions and managing the complications of iron overload was becoming a challenge to the family. They had learnt that Bone Marrow Transplant is the only cure for this condition. They began their search for a centre with immense experience in paediatric bone marrow transplants. Their research led to Narayana Health City in Bengaluru and Dr. Sunil Bhat who has remarkable experience in treating complex cases of blood disorders in children. The centre is also known for its innovative techniques in Haplo identical (half-matched) bone marrow transplants. Affirming that Bone Marrow Transplant (BMT) is the only cure for many life-threatening diseases, Dr. Sunil Bhat said, "With increasing number of haematological disorders, the number of patients requiring a blood stem cell transplant is also increasing. There are more than 1, 00,000 patients with serious blood disorders diagnosed in India every year and they can be cured with a BMT. One of the major differences between bone marrow transplant and solid organ transplants is that in BMT we need to match HLA of the patient and the donor. The chance of a patient finding a matched donor within family is only 25% to 30%; this leaves about 70% patients needing BMT for the cure of their disease but don't have a matching donor". The younger sister was fortunate as her brother was the HLA match who could donate, but he was only 11 months old! Extracting marrow stem cells from a donor who is an infant was a clinical challenge. The team at Narayana Health City came up with an innovative plan of taking the bone marrow from the donor at two different time points, around 4 to 6 weeks apart, in order to have adequate marrow for transplant. The transplant was performed in March this year making the 11-month-old infant the youngest donor to have donated bone marrow for his sister. The girl is completely cured of Thalassemia now. However, her elder sister was not so lucky as she couldn't get a fully matched donor. Therefore, her transplant was even more challenging. She did not have any HLA matched donor either in the family or anywhere in the World. The next possibility was a Haplo-identical transplant. Doctors at Mazumdar Shaw Cancer Centre at Narayana Health City decided to use the stem cells of the father who was a half match with the elder daughter. A new technique was used in haplo (half matched) transplant as the donor stem cells were not fully matching the patient. "Her bad cells were taken out in a procedure called TCR alpha-beta depletion and only the good cells were given to the patient", explained Dr. Sunil Bhat. "This avoids the risk of donor cells attacking the patient's body", he said. Although this technique helps in the above mentioned mechanism, it would delay the immune recovery, which would put them at risk of serious infections. "To address this issue of slow immune recovery, CD45RA depletion is an additional technique recently introduced", informed Dr. Sunil. "This helps us to give memory cells, which can fight infections in the patient", he said. This new technique has probably been used for the first time in India for the treatment of Thalassemia major.
Bengaluru, 30th August 2018: Department of Critical Care Medicine at Mazumdar Shaw Medical Center, Narayana Health City today organised a CME programme on the treatment of ARDS (adult respiratory distress syndrome) in ICU at its premises. The workshop witnessed around 120 delegates participating at the event from various specialties like physicians, pulmonologists, intensivists, anaesthesiologists and many allied science practitioners like respiratory and physiotherapists as well. Acute respiratory distress syndrome (ARDS) is a severe lung condition which occurs when fluid fills up the air sacs in lungs. Excess fluid in lungs can either lower the amount of oxygen or increase the amount of carbon dioxide in bloodstream. Further, ARDS can prevent oxygen supply to organs thereby restricting their function. In the worst sequel, it affects both the lungs to cause damage to alveoli (functional units of lung) which clinically manifest as difficulty in breathing, decreased oxygenation and failure of the respiratory system. Speaking about the event, Dr. M.M Harish, Consultant and academic In-charge, Department of Critical Care Medicine, Mazumdar Shaw Medical Center said, "The workshop was conducted to address recent rise in community acquired pneumonia and sepsis, which is one of the major cause among patients who require ICU admission these days. The rationale behind this program is to enlighten the knowledge on both basic pathophysiology of ARDS and advanced treatment options for deadly diseases like Extracorporeal Membrane Oxygenation (ECMO), prone position artificial ventilation and other newer methods of artificial respiration." With all the advances in medical technology, death rate because of ARDS still remains around 35-50%. ARDS can affect all the age groups from newborn to elderly with the spectrum of severity varying depending on how badly the patient is deprived of oxygen (hypoxia). Further, based on the degree of hypoxia, it is classified as mild, moderate and severe. More the degree of severity (i.e. hypoxia) more chances of death, therefore early recognition of the causative insult and hand in hand treatment of that cause and the ARDS parse is very important for saving a life. About Narayana Health City, Bengaluru: NH Health City is located in Bommasandra, Bengaluru, which comprises of Narayana Institute of Cardiac Sciences (NICS), a superspecialty hospital for cardiology and cardiac surgery, and Mazumdar Shaw Medical Center (MSMC), a multispecialty hospital for cancer care, neurology and neurosurgery, nephrology, urology, and houses what we believe, is one of India's largest bone marrow transplant units. NH Health City operates a stem cell bank.